The nameless protagonist of The Insects Unlisted in the Encyclopedia works for a trashy magazine called Black Book which attempts to publish stories about the bizarre happenings with the environs of Japan. One day his pretty albeit quite flatulent editor and chief tells him, under the threat of death, to find a substance called Deathfix which supposedly kills the individual, but after a few minutes the drug user comes back to life. The writer is supposed to take the drug, die, return to life, and then write about his experience being dead for his audience. The editor gives him a hefty sum to support his month long search. The first thing the writer does is enlist his buddy Endo to help him in his search. Endo, a modern day hippie and several years older than the writer, lives day to day in either a drug-induced or alcohol induced haze and busies himself trying to do things as create his own mermaid by tying the upper half of a doll to a fish. He also sets his own vomit on fire. With this being in tow, the writer goes in search of his cameraman Majima, but has little luck in doing so. The only clue he finds is a magnetic band. The writer and Endo's adventures continue and along the way they pick up a yakuza called Mr. Eyeball, a former dominatrix named Sayoko, and Mr. Eyeball's androgynous underling, things just continue to get stranger and stranger. However, maybe things get a bit too strange. While some of the gags found in The Insects Unlisted in the Encyclopedia are quite creative albeit disgusting and vulgar, they begin to grow old after awhile and with each gag trying to outdo the previous gag, it becomes just too much and the slender thread of the story evaporates.